Actin cytoskeleton and cell migration
Actin dynamics support cell shape, movement, repair and tissue development.
Biological pathway
Thymosin Beta-4 binds monomeric actin and influences actin polymerisation and cell migration.
Evidence summary
Mechanistic evidence is strong; clinical effects remain indication-specific.
Limitations
Peptides linked to this mechanism
TB-500 is an investigational peptide, analogue or research construct with evidence ranging from mechanistic studies to limited human trials.
Thymosin Beta 4 is an investigational peptide, analogue or research construct with evidence ranging from mechanistic studies to limited human trials.
RGDS Peptide is an investigational peptide, analogue or research construct with evidence ranging from mechanistic studies to limited human trials.
RGD Peptide is an investigational peptide, analogue or research construct with evidence ranging from mechanistic studies to limited human trials.
Thymosin Beta 10 is an investigational peptide, analogue or research construct with evidence ranging from mechanistic studies to limited human trials.